Tumor-to-function evidence for zebrafish cancer studies

Designed to connect longitudinal fluorescence tumor imaging with functional phenotype and tolerability in the same fish over time.

ONCOLOGY MODULE: VALIDATION IN BUILD

The platform's current initial validation wedge is CNS / ALS. Oncology remains a strategically important expansion module and will advance with customer-backed validation.

Why tumor burden alone is not enough

Tumor response is not the whole story

Tumor control with toxicity

A compound may reduce tumor burden while causing sedation, impaired locomotion, reduced feeding, or systemic toxicity.

Early functional warning

Behavioral changes may appear before a conventional tumor imaging endpoint becomes decisive.

Fragmented evidence

Tumor images, behavioral video, treatment records, controls, and study context are often reviewed in separate tools.

Product

The Tumor to Function Response Map

For each fish, SWARMOSCOPE is designed to create a longitudinal and reviewable profile containing tumor burden and dissemination trajectory, behavioral health trajectory, treatment response class, functional toxicity or confounding flag, model confidence, quality measures, and interpretable behavioral drivers.

Response classTumor imagingFunctional phenotypeResearch interpretation

True therapeutic responseTumor burden declinesBehavior remains stable or normalizesAnti-tumor activity with acceptable functional impact

Tumor control with toxicityTumor burden declines or stabilizesActivity, feeding, coordination, or sociality deteriorateApparent efficacy may be confounded by host toxicity

Nonresponse or progressionTumor burden grows or disseminatesProgressive behavioral deviationDisease-linked functional decline and possible early warning signal

Indeterminate / repeat requiredInsufficient or conflicting dataTracking confidence or coverage below thresholdRepeat or supplementary measurement required before a decision

Swarmoscope Oncology is being validated. We use language such as "designed to," "being validated," "aims to help," and "intended to distinguish." We do not claim that behavior predicts tumor response, reduces clinical failure, predicts human response, or diagnoses cancer. One fish. One identity. Two modalities. One auditable decision record.